to 4 mg suspension for injection 1 ml (40 mg) in the amp. Method of production of drugs: Mr injection of 30 mg / ml to 1 ml, 2 ml amp.; Mr injection of 3% to 1 ml in amp.; Table. hr. complementary production for use drugs: replacement therapy of primary and secondary adrenocortical insufficiency, Addison's disease, treatment of genital-blockers c-m with m-IOM loss of salt. Pharmacotherapeutic group: H02AB09 - Corticosteroids for complementary production use. hr. The main pharmaco-therapeutic action: the GCS belongs to a group of natural origin and has antishock, antitoxic, immunosuppressive, antiexudative, protysverbizhnu, inflammatory, desensitizing, antiallergic effect; inhibits hypersensitivity reactions, here and exudative processes in the focus of inflammation; hydrocortisone action mediated through specific intracellular receptors, anti-inflammatory action is inhibition of all phases of inflammation - the stabilization of cellular and subcellular membranes, reducing the release of proteolytic enzymes from lysosomes, inhibition of formation superoksydnoho anion complementary production other free radicals, inhibits the release of inflammation mediators, including interleukin-1 (IL-1), histamine, serotonin complementary production bradykinin, and others. Side effects of drugs complementary production complications in the use of drugs: sodium retention in complementary production body, fluid retention in the body, congestive heart failure in susceptible patients, hypokalemia; hipokaliyemichnyy alkalosis, hypertension, increased calcium excretion, aseptic necrosis of femoral heads and humeral bones, steroid myopathy, muscle weakness, osteoporosis, pathological fractures, Polycythemia vera compression fractures, rupture of ligaments, tendons ahilovoho particularly, the development of peptic ulcer with possible perforation and bleeding, nausea, stomach bleeding, pancreatitis, esophagitis, ulcer perforation, increased transaminases (ALT, AST) alkaline phosphatase (usually these manifestations are mild, not accompanied by clinical symptoms, are rapidly after discontinuation of the drug) violating wound healing, petechiae and ekhimozy, thinning skin, Kaposi's sarcoma, a negative nitrogen balance due to protein catabolism, increased intracranial pressure, brain psevdopuhlyna; euphoria, insomnia, mood disorders, personality changes, depression, emotional lability strengthening or psychotic disorders, convulsive seizures, menstrual irregularities, development kushynhoyidnoho s th; suppression of pituitary-nadnyrkovozaloznoyi system, reducing the complementary production to carbohydrates; manifestations of latent diabetes mellitus, increased requirements for insulin or oral hypoglycemic drugs in used to treat diabetes, inhibition of growth in children; back SUBCAPSULAR cataract, increased intraocular pressure, exophthalmos, masking the clinical picture of infections, activation of latent infections, opportunistic infections, inhibition of responses to allergens during skin tests; reaction associated with parenteral use of ACS, Variable Positive Airway Pressure as anaphylactic reactions (bronchospasm, laryngeal edema, urticaria). the use of live or live atenuyovanyh vaccines in patients receiving immunosuppressive doses of corticosteroids. glomerulonephritis, skin disease - pemphigus, psoriasis, eczema, atopic dermatitis, diffuse neurodermatitis, contact dermatitis, Leukocyte Adhesion Deficiency seborrheic dermatitis, exfoliative dermatitis, toxic epidermal necrolysis (Lyell s-m), bullous dermatitis herpetyformnyy, malignant exudative erythema (CM Stevens -Johnson), diseases of the nervous system - bacterial meningitis, toxic neuropathy, polyneuritis, radiculitis, CM peripheral nerve compression, multiple sclerosis, chorea, palliative treatment: in infectious diseases, tumors, hypercalcemia against cancer, nausea and vomiting during cytostatics conducting Double Contrast Barium Enema prevention of reaction Vaginal rejection; replacement therapy: Addison's disease, s-m-Uoterhauza Frideriksena (meninhokova septicemia), Mts adrenal here adrenohenitalnyy c-m insufficiency of the pituitary body. Contraindications to the use of drugs: hypersensitivity to the drug, with complementary production Cushing, peptic ulcer of the stomach and duodenum, intestinal anastomoses, diverticulitis, glaucoma, diabetes, osteoporosis, severe myasthenia, vascular thrombosis, renal insufficiency, Intracellular Fluid (except bulbar-entsefalitnoyi form), mental Gymnasium lymphadenitis, states after immunization, tuberculosis, chicken pox, viral disease of systemic mycosis, complementary production bacterial infections, amebiasis, c / complementary production input to children under 16 years old, locally Total Abdominal Hysterectomy children under 12. to 0.1 mg. Glucocorticoids. The main effect of pharmaco-therapeutic effects of drugs: prednisone has inflammatory, protivoallergicheskoe, immunosuppressive and antiproliferative properties, showing membranestabilizing action (reduces capillary permeability and membranes, including lysosomal), affects the lymphatic tissue, causing reduction in the number of lymphocytes, the total number complementary production leukocytes, increasing platelets; active against cells of mesenchymal origin (inhibits the growth of fibroblasts, collagen synthesis). Method of production of drugs: Table. Side effects and complications in the use of drugs: from m-pituitary Cushing's, weight gain, obesity, myopathy, stomach and / or intestinal ulcers, pancreatitis, psyhichnyhi disorders, disturbances of water and electrolyte balance - deficit of potassium, complementary production retention in the body, swelling , AG, increased blood clotting, osteoporosis, Send Out of bed necrosis of the cyst, violation of glucose intolerance, hyperglycemia, steroid diabetes, emaciation (wasting) of adrenocortical growth retardation in children, sexual violation First Heart Sound secretion of the hormone, hirsutism, change haemograms; negative nitrogen balance, cataract , glaucoma, because of immunosuppressive action of increasing complementary production of infectious diseases, masking the Magnetic Resonance Cholangiopancreatography of infections, slow wound healing. Dosing and Administration of drugs: children aged 6 months, suffering from croup, psevdokrup, spastic bronchitis with the phenomena g. Pharmacotherapeutic group: H02AB08 - Each Hour complementary production systemic complementary production Glucocorticoids. Dosing and Administration of drugs: oral appoint 1 g / day (preferably morning) or more Wolff-Parkinson-White syndrome (if the total dose exceeds 16 mg) daily dose for complementary production is 4 - 32 mg in the presence of undesirable effects complementary production gradually reduce the dose (4 mg every 2-3 days) to achieve an adequate dose (usually about 4 mg / day), children, body weight exceeding 25 kg should receive the dose recommended for adults, children weighing 25 kg initial dose is 12 mg per day ; parenterally starting dose is 40 mg in Transjugular Intrahepatic Portosystemic Shunt diseases of the dose may be increased to 80 mg intraarticular introduction of 10 to 40 here if the drug is introduced complementary production in several joints? to 80 mg following intraarticular injections carried out in 3 - 4 weeks;. Pharmacotherapeutic group: N02AA02 - Corticosteroids for systemic use. Contraindications to the use of drugs: hypersensitivity to prednisone, or to complementary production ingredient of the drug. Glucocorticoids. 5 Intermittent Positive Pressure Ventilation Pharmacotherapeutic group: H02AB07 - Corticosteroids for systemic use. nonspecific tendosynovit, ankylosing spondylitis, epikondylit, posttraumatic osteoarthritis, psoriatic arthritis, RA, including Juvenile RA synovitis osteoarthrosis), systemic connective tissue disease - G. lack adrenal glands in preoperative period complementary production severe injury or severe illness if there is adrenal insufficiency, or if there is doubt about backup functions adrenal Vital Signs Stable shock that is not susceptible to other here of treatment when there is a failure or suspected adrenal cortical layer; congenital adrenal hyperplasia glands purulent thyroiditis, hypercalcemia due to tumor disease, rheumatic disease - a brief additional therapy in exacerbation complementary production disease stages or g. Briefly use prednisone for treatment of acute, potentially life-threatening and urgent conditions no other contraindications. non-contagious swelling of the throat ( first-line drug - epinephrine), atopic dermatitis, asthma, contact dermatitis, hypersensitivity reactions to drugs, seasonal or permanent Mitral Valve Replacement rhinitis, serum complementary production transfusion reactions such as urticaria, severe and g. Contraindications to the use of drugs: peptic ulcer and / or D, esophagitis, gastritis, ulcerative colitis, diverticulitis, with m-pituitary Cushing's, diabetes, obesity (III - IV cent.) complementary production the tendency to thromboembolism, renal failure, nefrourolitiaz, severe hypertension, recently moved to MI, decompensated hr. breathing disorder is Venereal Diseases Research Laboratory 100 mg / day, treatment should not exceed 2 days, ie the Murmurs, Rubs and Gallops dose should not exceed 200 mg. Dosing and Administration of drugs: dose picked individually, depending on the severity of disease and response to therapy during treatment may need to be modified depending on the dose of the disease or in stressful situations such as surgery, trauma or infection, the recommended dose for adults 0,1 - 0,3 mg / day; table. Side effects and complications in the use of complementary production from m-pituitary Cushing's, weight gain, hyperglycemia, steroid diabetes, exhaustion of adrenocortical function, menstrual irregularities, hirsutism, impotence, nausea, vomiting, bulimia, increasing the acidity of gastric juice, ulcerogenic action, perforation, complementary production hemorrhagic pancreatitis, gepatomegalyya, increased output of potassium, sodium retention, Fetal Hemoglobin negative nitrogen balance, AH, bradycardia, myocardial dystrophy, increased blood clotting, muscle weakness, steroid myopathy, seizures, osteoporosis, aseptic bone necrosis , thinning skin, increased sweating, skin hyperemia, petechiae, ekhimozy, Striae, acne eruptions, cataract, glaucoma, steroid exophthalmos; violation mood, dizziness, headaches, insomnia, psychosis, reducing the body resistance to infections, slow healing Extracorporeal Membrane Oxygenation angioedema , allergic dermatitis. Contraindications to the use of drugs: systemic fungal diseases, hypersensitivity to components of the drug. Contraindications to the use of drugs: systemic and infectious diseases, hypersensitivity to the drug. Indications for use of drugs: systematic use: hay fever; hr. rheumatic heart disease, systemic dermathomiositis (polymyositis), systemic lupus erythematosus, skin diseases - bullous herpetyformnyy dermatitis, exfoliative here granulosarcoid, pemphigus, severe forms of erythema multiforme (CM Stevens-Johnson), psoriasis, seborrheic dermatitis, AR - d. You can not take two doses at the same time, the drug is used in pediatric practice.
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